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Obstructive sleep apnea aggravates neuroinflammation and pyroptosis in early brain injury following subarachnoid hemorrhage via ASC/HIF-1α pathway

Obstructive sleep apnea can worsen the prognosis of subarachnoid hemorrhage. However, the underlying mechanism remains unclear. In this study, we established a mouse model of subarachnoid hemorrhage using the endovascular perforation method and exposed the mice to intermittent hypoxia for 8 hours da...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Li, Qian, Xu, Chen-Yu, Mao, Shan, Jin, Jia-Jia, Gu, Wei, Shi, Ying, Zou, Chun-Fang, Ye, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120669/
https://www.ncbi.nlm.nih.gov/pubmed/35535908
http://dx.doi.org/10.4103/1673-5374.339000