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Visualization of the binding between gintonin, a Panax ginseng-derived LPA receptor ligand, and the LPA receptor subtypes and transactivation of the EGF receptor

BACKGROUND: Gintonin is a ginseng-derived exogenous G-protein-coupled lysophosphatidic acid (LPA) receptor ligand. Gintonin exerts its neuronal and non-neuronal in vitro and in vivo effects through LPA receptor subtypes. However, it is unknown whether gintonin can bind to the plasma membrane of cell...

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Detalles Bibliográficos
Autores principales: Choi, Sun-Hye, Lee, Ra Mi, Cho, Han-Sung, Hwang, Sung Hee, Hwang, Hong-Ik, Rhim, Hyewhon, Kim, Hyoung-Chun, Kim, Do-Geun, Cho, Ik-Hyun, Nah, Seung-Yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120792/
https://www.ncbi.nlm.nih.gov/pubmed/35600777
http://dx.doi.org/10.1016/j.jgr.2021.10.004