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Cross-Talk Between Histone Methyltransferases and Demethylases Regulate REST Transcription During Neurogenesis

The RE1 Silencing Transcription Factor (REST) is a major regulator of neurogenesis and brain development. Medulloblastoma (MB) is a pediatric brain cancer characterized by a blockade of neuronal specification. REST gene expression is aberrantly elevated in a subset of MBs that are driven by constitu...

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Detalles Bibliográficos
Autores principales: Swaminathan, Jyothishmathi, Maegawa, Shinji, Shaik, Shavali, Sharma, Ajay, Bravo-Alegria, Javiera, Guo, Lei, Xu, Lin, Harmanci, Arif, Gopalakrishnan, Vidya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120943/
https://www.ncbi.nlm.nih.gov/pubmed/35600406
http://dx.doi.org/10.3389/fonc.2022.855167