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Treatment With an Angiopoietin-1 Mimetic Peptide Improves Cognitive Outcome in Rats With Vascular Dementia

BACKGROUND AND PURPOSE: Vascular dementia (VaD) is a complex neurodegenerative disease affecting cognition and memory. There is a lack of approved pharmacological treatments specifically for VaD. In this study, we investigate the therapeutic effects of AV-001, a Tie2 receptor agonist, in middle-aged...

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Detalles Bibliográficos
Autores principales: Culmone, Lauren, Powell, Brianna, Landschoot-Ward, Julie, Zacharek, Alex, Gao, Huanjia, Findeis, Elizabeth L., Malik, Ayesha, Lu, Mei, Chopp, Michael, Venkat, Poornima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120946/
https://www.ncbi.nlm.nih.gov/pubmed/35602559
http://dx.doi.org/10.3389/fncel.2022.869710