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LincRNA-EPS increases TGF-β expression to inhibit the Wnt/β-catenin pathway, VSMC osteoblastic differentiation and vascular calcification in diabetic mice

In patients with diabetes, the Wnt/β-catenin pathway in vascular smooth muscle cells (VSMCs) is continuously activated by low-intensity inflammation, which leads to the osteoblastic differentiation of these cells and the deposition of calcium and phosphorus in blood vessels. The aim of the present s...

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Detalles Bibliográficos
Autores principales: Li, Yibo, Xi, Ziwei, Yu, Zheng, Yang, Chaoyue, Tan, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121197/
https://www.ncbi.nlm.nih.gov/pubmed/35607373
http://dx.doi.org/10.3892/etm.2022.11352