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Polyploid giant cancer cells, EZH2 and Myc upregulation in mammary epithelial cells infected with high-risk human cytomegalovirus

BACKGROUND: Human cytomegalovirus (HCMV) infection has been actively implicated in complex neoplastic processes. Beyond oncomodulation, the molecular mechanisms that might underlie HCMV-induced oncogenesis are being extensively studied. Polycomb repressive complex 2 (PRC2) proteins, in particular en...

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Detalles Bibliográficos
Autores principales: Nehme, Zeina, Pasquereau, Sébastien, Haidar Ahmad, Sandy, El Baba, Ranim, Herbein, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121245/
https://www.ncbi.nlm.nih.gov/pubmed/35596973
http://dx.doi.org/10.1016/j.ebiom.2022.104056