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The Taspase1/Myosin1f-axis regulates filopodia dynamics

The unique threonine protease Tasp1 impacts not only ordered development and cell proliferation but also pathologies. However, its substrates and the underlying molecular mechanisms remain poorly understood. We demonstrate that the unconventional Myo1f is a Tasp1 substrate and unravel the physiologi...

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Detalles Bibliográficos
Autores principales: Hensel, Astrid, Stahl, Paul, Moews, Lisa, König, Lena, Patwardhan, Rutuja, Höing, Alexander, Schulze, Nina, Nalbant, Perihan, Stauber, Roland H., Knauer, Shirley K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121324/
https://www.ncbi.nlm.nih.gov/pubmed/35601920
http://dx.doi.org/10.1016/j.isci.2022.104355