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HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence

During metastasis cancer cells must adapt to survive loss of anchorage and evade anoikis. An important pro-survival adaptation is the ability of metastatic tumor cells to increase their antioxidant capacity and restore cellular redox balance. Although much is known about the transcriptional regulati...

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Detalles Bibliográficos
Autores principales: Kim, Yeon Soo, Tang, Priscilla W., Welles, Jaclyn E., Pan, Weihua, Javed, Zaineb, Elhaw, Amal Taher, Mythreye, Karthikeyan, Kimball, Scot R., Hempel, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121325/
https://www.ncbi.nlm.nih.gov/pubmed/35594792
http://dx.doi.org/10.1016/j.redox.2022.102329