Cargando…

Small Extracellular Vesicles in Milk Cross the Blood-Brain Barrier in Murine Cerebral Cortex Endothelial Cells and Promote Dendritic Complexity in the Hippocampus and Brain Function in C57BL/6J Mice

Human milk contains large amounts of small extracellular vesicles (sEVs) and their microRNA cargos, whereas infant formulas contain only trace amounts of sEVs and microRNAs. We assessed the transport of sEVs across the blood-brain barrier (BBB) and sEV accumulation in distinct regions of the brain i...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Fang, Ebea, Pearl, Mutai, Ezra, Wang, Haichuan, Sukreet, Sonal, Navazesh, Shya, Dogan, Haluk, Li, Wenhao, Cui, Juan, Ji, Peng, Ramirez, Denise M. O., Zempleni, Janos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121399/
https://www.ncbi.nlm.nih.gov/pubmed/35600828
http://dx.doi.org/10.3389/fnut.2022.838543