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Small Extracellular Vesicles in Milk Cross the Blood-Brain Barrier in Murine Cerebral Cortex Endothelial Cells and Promote Dendritic Complexity in the Hippocampus and Brain Function in C57BL/6J Mice
Human milk contains large amounts of small extracellular vesicles (sEVs) and their microRNA cargos, whereas infant formulas contain only trace amounts of sEVs and microRNAs. We assessed the transport of sEVs across the blood-brain barrier (BBB) and sEV accumulation in distinct regions of the brain i...
Autores principales: | Zhou, Fang, Ebea, Pearl, Mutai, Ezra, Wang, Haichuan, Sukreet, Sonal, Navazesh, Shya, Dogan, Haluk, Li, Wenhao, Cui, Juan, Ji, Peng, Ramirez, Denise M. O., Zempleni, Janos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121399/ https://www.ncbi.nlm.nih.gov/pubmed/35600828 http://dx.doi.org/10.3389/fnut.2022.838543 |
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