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Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine

Despite success in vaccinating populations against SARS-CoV-2, concerns about immunity duration, continued efficacy against emerging variants, protection from infection and transmission, and worldwide vaccine availability remain. Molecular adjuvants targeting pattern recognition receptors (PRRs) on...

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Detalles Bibliográficos
Autores principales: Atalis, Alexandra, Keenum, Mark C., Pandey, Bhawana, Beach, Alexander, Pradhan, Pallab, Vantucci, Casey, O'Farrell, Laura, Noel, Richard, Jain, Ritika, Hosten, Justin, Smith, Clinton, Kramer, Liana, Jimenez, Angela, Ochoa, Miguel Armenta, Frey, David, Roy, Krishnendu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121740/
https://www.ncbi.nlm.nih.gov/pubmed/35577151
http://dx.doi.org/10.1016/j.jconrel.2022.05.023