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Blood HDAC4 Variation Links With Disease Activity and Response to Tumor Necrosis Factor Inhibitor and Regulates CD4+ T Cell Differentiation in Ankylosing Spondylitis

PURPOSE: Histone deacetylase 4 (HDAC4) regulates the progression of autoimmune diseases. This study aimed to further investigate the correlation between HDAC4 and Th cells, inflammation, disease activity, and treatment response in patients with ankylosing spondylitis (AS). METHODS: A total of 132 ac...

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Detalles Bibliográficos
Autores principales: Dou, Bin, Ma, Fuzhe, Jiang, Zhenyu, Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121817/
https://www.ncbi.nlm.nih.gov/pubmed/35602496
http://dx.doi.org/10.3389/fmed.2022.875341