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Flagellin/Virus-like Particle Hybrid Platform with High Immunogenicity, Safety, and Versatility for Vaccine Development

[Image: see text] Hepatitis B core (HBc) virus-like particles (VLPs) and flagellin are highly immunogenic and widely explored vaccine delivery platforms. Yet, HBc VLPs mainly allow the insertion of relatively short antigenic epitopes into the immunodominant c/e1 loop without affecting VLP assembly,...

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Detalles Bibliográficos
Autores principales: Zhao, Yiwen, Li, Zhuofan, Voyer, Jewel, Li, Yibo, Chen, Xinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121874/
https://www.ncbi.nlm.nih.gov/pubmed/35467839
http://dx.doi.org/10.1021/acsami.2c01028