Pharmacokinetics, pharmacodynamics, and safety of verinurad with and without allopurinol in healthy Asian, Chinese, and non‐Asian participants

Verinurad is a selective inhibitor of uric acid transporter 1 (URAT1). Here, we assessed the safety, pharmacokinetics, and pharmacodynamics of verinurad + allopurinol and verinurad monotherapy in healthy participants. Studies 1 (NCT03836599) and 2 (NCT02608710) were randomized Phase 1 studies. In St...

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Detalles Bibliográficos
Autores principales: Johansson, Susanne, Han, David, Hunt, Thomas, Björck, Karin, Florica, Delia, Gillen, Michael, Hall, Jesse, Erlandsson, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121888/
https://www.ncbi.nlm.nih.gov/pubmed/35593744
http://dx.doi.org/10.1002/prp2.929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121888/
https://www.ncbi.nlm.nih.gov/pubmed/35593744
http://dx.doi.org/10.1002/prp2.929

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