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Silibinin Schiff Base Derivatives Counteract CCl(4)-Induced Acute Liver Injury by Enhancing Anti-Inflammatory and Antiapoptotic Bioactivities
BACKGROUND: Silibinin (Sil), a flavonoid lignan-like natural compound derived from milk thistle seeds, has been used to treat hepatic diseases, including early-phase hepatocirrhosis and fatty liver, for many years. However, its poor water solubility limits its gastrointestinal absorption and bioavai...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122151/ https://www.ncbi.nlm.nih.gov/pubmed/35601675 http://dx.doi.org/10.2147/DDDT.S356847 |