Silibinin Schiff Base Derivatives Counteract CCl(4)-Induced Acute Liver Injury by Enhancing Anti-Inflammatory and Antiapoptotic Bioactivities

BACKGROUND: Silibinin (Sil), a flavonoid lignan-like natural compound derived from milk thistle seeds, has been used to treat hepatic diseases, including early-phase hepatocirrhosis and fatty liver, for many years. However, its poor water solubility limits its gastrointestinal absorption and bioavai...

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Detalles Bibliográficos
Autores principales: Xu, Rong, Qiu, Siyan, Zhang, Jie, Liu, Xiaoli, Zhang, Ling, Xing, Haizhu, You, Min, Wang, Man, Lu, Yuting, Zhang, Peng, Zhu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122151/
https://www.ncbi.nlm.nih.gov/pubmed/35601675
http://dx.doi.org/10.2147/DDDT.S356847

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