P2X4 receptors mediate induction of antioxidants, fibrogenic cytokines and ECM transcripts; in presence of replicating HCV in in vitro setting: An insight into role of P2X4 in fibrosis

BACKGROUND & AIMS: Major HCV infections lead to chronic hepatitis, which results in progressive liver disease including fibrosis, cirrhosis and eventually hepatocellular carcinoma (HCC). P2X4 and P2X7 are most widely distributed receptors on hepatocytes. METHODS: Full length P2X4 (1.7kb) (Rattus...

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Detalles Bibliográficos
Autores principales: Manzoor, Sobia, Khalid, Madiha, Idrees, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122194/
https://www.ncbi.nlm.nih.gov/pubmed/35594248
http://dx.doi.org/10.1371/journal.pone.0259727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122194/
https://www.ncbi.nlm.nih.gov/pubmed/35594248
http://dx.doi.org/10.1371/journal.pone.0259727

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