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Effective protection of ZF2001 against the SARS-CoV-2 Delta variant in lethal K18-hACE2 mice

To investigate the protective efficacy and mechanism of ZF2001 (a protein subunit vaccine with conditional approval in China) to SARS-CoV-2 Delta variant-induced severe pneumonia, the lethal challenge model of K18-hACE2 transgenic mice was used in this study. An inactivated-virus vaccine at the rese...

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Detalles Bibliográficos
Autores principales: Bian, Lianlian, Bai, Yu, Gao, Fan, Liu, Mingchen, He, Qian, Wu, Xing, Mao, Qunying, Xu, Miao, Liang, Zhenglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122244/
https://www.ncbi.nlm.nih.gov/pubmed/35596222
http://dx.doi.org/10.1186/s12985-022-01818-x