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Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Mycobacterium tuberculosis lung infection results in a complex multicellular structure: the granuloma. In some granulomas, immune activity promotes bacterial clearance, but in others, bacteria persist and grow. We identified correlates of bacterial control in cynomolgus macaque lung granulomas by co...

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Detalles Bibliográficos
Autores principales: Gideon, Hannah P., Hughes, Travis K., Tzouanas, Constantine N., Wadsworth, Marc H., Tu, Ang Andy, Gierahn, Todd M., Peters, Joshua M., Hopkins, Forrest F., Wei, Jun-Rong, Kummerlowe, Conner, Grant, Nicole L., Nargan, Kievershen, Phuah, Jia Yao, Borish, H. Jacob, Maiello, Pauline, White, Alexander G., Winchell, Caylin G., Nyquist, Sarah K., Ganchua, Sharie Keanne C., Myers, Amy, Patel, Kush V., Ameel, Cassaundra L., Cochran, Catherine T., Ibrahim, Samira, Tomko, Jaime A., Frye, Lonnie James, Rosenberg, Jacob M., Shih, Angela, Chao, Michael, Klein, Edwin, Scanga, Charles A., Ordovas-Montanes, Jose, Berger, Bonnie, Mattila, Joshua T., Madansein, Rajhmun, Love, J. Christopher, Lin, Philana Ling, Leslie, Alasdair, Behar, Samuel M., Bryson, Bryan, Flynn, JoAnne L., Fortune, Sarah M., Shalek, Alex K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122264/
https://www.ncbi.nlm.nih.gov/pubmed/35483355
http://dx.doi.org/10.1016/j.immuni.2022.04.004