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Astragalus injection ameliorates lipopolysaccharide-induced cognitive decline via relieving acute neuroinflammation and BBB damage and upregulating the BDNF-CREB pathway in mice

CONTEXT: Post-sepsis cognitive impairment is one of the major sequelae observed in survivors of sepsis. Astragalus injection is the normally preferred treatment in sepsis in clinical settings. OBJECTIVE: This study evaluated the benefits and related mechanism of Astragalus injection on post-sepsis c...

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Detalles Bibliográficos
Autores principales: Liu, Ke, Wan, Guoran, Jiang, Ruhong, Zou, Li, Wan, Dong, Zhu, Huifeng, Feng, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122367/
https://www.ncbi.nlm.nih.gov/pubmed/35587259
http://dx.doi.org/10.1080/13880209.2022.2062005