Fraxinol attenuates LPS-induced acute lung injury by equilibrating ACE-Ang II-AT1R and ACE2-Ang (1-7)-Mas and inhibiting NLRP3

CONTEXT: Acute lung injury (ALI) is a serious heterogenous pulmonary disorder. Fraxinol was selected for this study since it is a simple coumarin compound, not previously investigated in ALI. OBJECTIVES: This study investigates the ALI therapeutic effect and mechanisms of fraxinol. MATERIALS AND MET...

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Detalles Bibliográficos
Autores principales: Wu, Yan, Yang, Xin, Ju, Yuanyuan, Zhao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122403/
https://www.ncbi.nlm.nih.gov/pubmed/35588103
http://dx.doi.org/10.1080/13880209.2022.2067571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122403/
https://www.ncbi.nlm.nih.gov/pubmed/35588103
http://dx.doi.org/10.1080/13880209.2022.2067571

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