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G2/M arrest and mitotic slippage induced by fenbendazole in canine melanoma cells

BACKGROUND: The use of fenbendazole (FBZ) in terminal cancer patients has recently increased, as anthelminthic drugs, such as FBZ and benzimidazole, exhibit anti‐tubulin effects in tumour cells. OBJECTIVES: The present study evaluated the in vitro anti‐cancer effects of FBZ in five canine melanoma c...

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Detalles Bibliográficos
Autores principales: Kim, Sehoon, Perera, Shashini Kanchanamala, Choi, Seo‐In, Rebhun, Robert B., Seo, Kyoung‐won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122462/
https://www.ncbi.nlm.nih.gov/pubmed/35020278
http://dx.doi.org/10.1002/vms3.733