DNA-PK promotes DNA end resection at DNA double strand breaks in G(0) cells

DNA double-strand break (DSB) repair by homologous recombination is confined to the S and G(2) phases of the cell cycle partly due to 53BP1 antagonizing DNA end resection in G(1) phase and non-cycling quiescent (G(0)) cells where DSBs are predominately repaired by non-homologous end joining (NHEJ)....

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Detalles Bibliográficos
Autores principales: Fowler, Faith C, Chen, Bo-Ruei, Zolnerowich, Nicholas, Wu, Wei, Pavani, Raphael, Paiano, Jacob, Peart, Chelsea, Chen, Zulong, Nussenzweig, André, Sleckman, Barry P, Tyler, Jessica K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122494/
https://www.ncbi.nlm.nih.gov/pubmed/35575473
http://dx.doi.org/10.7554/eLife.74700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122494/
https://www.ncbi.nlm.nih.gov/pubmed/35575473
http://dx.doi.org/10.7554/eLife.74700

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