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C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9

The proinflammatory alarmins S100A8 and S100A9 are among the most abundant proteins in neutrophils and monocytes but are completely silenced after differentiation to macrophages. The molecular mechanisms of the extraordinarily dynamic transcriptional regulation of S100a8 and S100a9 genes, however, a...

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Detalles Bibliográficos
Autores principales: Jauch-Speer, Saskia-Larissa, Herrera-Rivero, Marisol, Ludwig, Nadine, Véras De Carvalho, Bruna Caroline, Martens, Leonie, Wolf, Jonas, Imam Chasan, Achmet, Witten, Anika, Markus, Birgit, Schieffer, Bernhard, Vogl, Thomas, Rossaint, Jan, Stoll, Monika, Roth, Johannes, Fehler, Olesja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122501/
https://www.ncbi.nlm.nih.gov/pubmed/35543413
http://dx.doi.org/10.7554/eLife.75594