Quantification of Usaramine and its N-Oxide Metabolite in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry

A sensitive, fast and robust liquid chromatography--tandem mass spectrometry (LC–MS-MS) method was developed and validated for the determination of usaramine (URM) and usaramine N-oxide (UNO) in rat plasma. The separation was conducted on an ACQUITY UPLC BEH C(18) Column (50 × 2.1 mm, 1.7 μm) and gr...

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Detalles Bibliográficos
Autores principales: Lin, Feifei, Ma, Yan, Pan, Anni, Ye, Yang, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122504/
https://www.ncbi.nlm.nih.gov/pubmed/34086913
http://dx.doi.org/10.1093/jat/bkab060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122504/
https://www.ncbi.nlm.nih.gov/pubmed/34086913
http://dx.doi.org/10.1093/jat/bkab060

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