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Quantification of Usaramine and its N-Oxide Metabolite in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry
A sensitive, fast and robust liquid chromatography--tandem mass spectrometry (LC–MS-MS) method was developed and validated for the determination of usaramine (URM) and usaramine N-oxide (UNO) in rat plasma. The separation was conducted on an ACQUITY UPLC BEH C(18) Column (50 × 2.1 mm, 1.7 μm) and gr...
Autores principales: | Lin, Feifei, Ma, Yan, Pan, Anni, Ye, Yang, Liu, Jia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122504/ https://www.ncbi.nlm.nih.gov/pubmed/34086913 http://dx.doi.org/10.1093/jat/bkab060 |
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