DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations

Structural Maintenance of Chromosomes (SMC) complexes play essential roles in genome organization across all domains of life. To determine how the activities of these large (≈50 nm) complexes are controlled by ATP binding and hydrolysis, we developed a molecular dynamics model that accounts for conf...

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Detalles Bibliográficos
Autores principales: Nomidis, Stefanos K, Carlon, Enrico, Gruber, Stephan, Marko, John F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122525/
https://www.ncbi.nlm.nih.gov/pubmed/35474142
http://dx.doi.org/10.1093/nar/gkac268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122525/
https://www.ncbi.nlm.nih.gov/pubmed/35474142
http://dx.doi.org/10.1093/nar/gkac268

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