Reovirus μ2 protein modulates host cell alternative splicing by reducing protein levels of U5 snRNP core components

Mammalian orthoreovirus (MRV) is a double-stranded RNA virus from the Reoviridae family presenting a promising activity as an oncolytic virus. Recent studies have underlined MRV’s ability to alter cellular alternative splicing (AS) during infection, with a limited understanding of the mechanisms at...

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Detalles Bibliográficos
Autores principales: Boudreault, Simon, Durand, Mathieu, Martineau, Carole-Anne, Perreault, Jean-Pierre, Lemay, Guy, Bisaillon, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122528/
https://www.ncbi.nlm.nih.gov/pubmed/35489070
http://dx.doi.org/10.1093/nar/gkac272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122528/
https://www.ncbi.nlm.nih.gov/pubmed/35489070
http://dx.doi.org/10.1093/nar/gkac272

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