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Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit

The −1 programmed ribosomal frameshifting (−1 PRF) has been explored as a gene regulatory circuit for synthetic biology applications. The −1 PRF usually uses an RNA pseudoknot structure as the frameshifting stimulator. Finding a ligand-responsive pseudoknot with efficient −1 PRF activity is time con...

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Detalles Bibliográficos
Autores principales: Hsu, Hsiu-Ting, Murata, Asako, Dohno, Chikara, Nakatani, Kazuhiko, Chang, KungYao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122530/
https://www.ncbi.nlm.nih.gov/pubmed/35511080
http://dx.doi.org/10.1093/nar/gkac257