Pan-cancer assessment of mutational landscape in intrinsically disordered hotspots reveals potential driver genes

Large-scale cancer genome sequencing has enabled the catalogs of somatic mutations; however, the mutational impact on intrinsically disordered protein regions (IDRs) has not been systematically investigated to date. Here, we comprehensively characterized the mutational landscapes of IDRs and found t...

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Detalles Bibliográficos
Autores principales: Zou, Haozhe, Pan, Tao, Gao, Yueying, Chen, Renwei, Li, Si, Guo, Jing, Tian, Zhanyu, Xu, Gang, Xu, Juan, Ma, Yanlin, Li, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122534/
https://www.ncbi.nlm.nih.gov/pubmed/35061901
http://dx.doi.org/10.1093/nar/gkac028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122534/
https://www.ncbi.nlm.nih.gov/pubmed/35061901
http://dx.doi.org/10.1093/nar/gkac028

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