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Nearest neighbor rules for RNA helix folding thermodynamics: improved end effects

Nearest neighbor parameters for estimating the folding stability of RNA secondary structures are in widespread use. For helices, current parameters penalize terminal AU base pairs relative to terminal GC base pairs. We curated an expanded database of helix stabilities determined by optical melting e...

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Detalles Bibliográficos
Autores principales: Zuber, Jeffrey, Schroeder, Susan J, Sun, Hongying, Turner, Douglas H, Mathews, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122537/
https://www.ncbi.nlm.nih.gov/pubmed/35524574
http://dx.doi.org/10.1093/nar/gkac261