Targeted delivery to macrophages and dendritic cells by chemically modified mannose ligand-conjugated siRNA

Extrahepatic delivery of small interfering RNAs (siRNAs) may have applications in the development of novel therapeutic approaches. However, reports on such approaches are limited, and the scarcity of reports concerning the systemically targeted delivery of siRNAs with effective gene silencing activi...

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Detalles Bibliográficos
Autores principales: Uehara, Keiji, Harumoto, Toshimasa, Makino, Asana, Koda, Yasuo, Iwano, Junko, Suzuki, Yasuhiro, Tanigawa, Mari, Iwai, Hiroto, Asano, Kana, Kurihara, Kana, Hamaguchi, Akinori, Kodaira, Hiroshi, Atsumi, Toshiyuki, Yamada, Yoji, Tomizuka, Kazuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122583/
https://www.ncbi.nlm.nih.gov/pubmed/35524566
http://dx.doi.org/10.1093/nar/gkac308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122583/
https://www.ncbi.nlm.nih.gov/pubmed/35524566
http://dx.doi.org/10.1093/nar/gkac308

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