NASP maintains histone H3–H4 homeostasis through two distinct H3 binding modes

Histone chaperones regulate all aspects of histone metabolism. NASP is a major histone chaperone for H3–H4 dimers critical for preventing histone degradation. Here, we identify two distinct histone binding modes of NASP and reveal how they cooperate to ensure histone H3–H4 supply. We determine the s...

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Detalles Bibliográficos
Autores principales: Bao, Hongyu, Carraro, Massimo, Flury, Valentin, Liu, Yanhong, Luo, Min, Chen, Liu, Groth, Anja, Huang, Hongda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122598/
https://www.ncbi.nlm.nih.gov/pubmed/35489058
http://dx.doi.org/10.1093/nar/gkac303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122598/
https://www.ncbi.nlm.nih.gov/pubmed/35489058
http://dx.doi.org/10.1093/nar/gkac303

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