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Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways

BACKGROUND: Testosterone deficiency is reportedly correlated with an elevation of cholesterol in plasma, but the mechanism remains unclear. Our objective was to investigate the effects of testosterone deficiency on cholesterol metabolism and the corresponding molecular changes in vivo and in vitro....

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Detalles Bibliográficos
Autores principales: Yuefeng, Yu, Zhiqi, Lin, Yi, Chen, Keyu, Zhu, Heng, Wan, Yuying, Wang, Ningjian, Wang, Yuetian, Yu, Xinjie, Gu, Yihao, Zhang, Yingli, Lu, Fangzhen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122719/
https://www.ncbi.nlm.nih.gov/pubmed/35599686
http://dx.doi.org/10.1155/2022/7989751