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Noise reduction by upstream open reading frames

Gene expression is prone to burst production, making it a highly noisy process that requires additional controls. Upstream open reading frames (uORFs) are widely present in the 5′ leader sequences of 30–50% of eukaryotic messenger RNAs(1–3). The translation of uORFs can repress the translation effic...

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Detalles Bibliográficos
Autores principales:	Wu, Ho-Wei, Fajiculay, Erickson, Wu, Jing-Fen, Yan, Ching-Cher Sanders, Hsu, Chao-Ping, Wu, Shu-Hsing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122824/ https://www.ncbi.nlm.nih.gov/pubmed/35501454 http://dx.doi.org/10.1038/s41477-022-01136-8

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