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Expression, Purification, Characterization and Cellular Uptake of MeCP2 Variants

The transcriptional regulator Methyl-CpG-binding protein 2 (MeCP2) is an intrinsically disordered protein, mutations in which, are implicated in the onset of Rett Syndrome, a severe and debilitating neurodevelopmental disorder. Delivery of this protein fused to the cell-penetrating peptide TAT could...

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Detalles Bibliográficos
Autores principales: Beribisky, Alexander V., Steinkellner, Hannes, Geislberger, Sofia, Huber, Anna, Sarne, Victoria, Christodoulou, John, Laccone, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122891/
https://www.ncbi.nlm.nih.gov/pubmed/35546650
http://dx.doi.org/10.1007/s10930-022-10054-9