Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E(2)-dependent growth of ER-positive breast cancer

Although type I interferons (IFNs) play multifaceted roles during tumorigenesis and cancer treatment, the interplay between type I IFNs and estrogen signaling in breast cancer (BC) microenvironment is not well understood. Here, we report a novel function of type I IFNs in inducing aromatase expressi...

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Detalles Bibliográficos
Autores principales: Ka, Na-Lee, Lim, Ga Young, Kim, Seung‑Su, Hwang, Sewon, Han, Juhyeong, Lee, Yun-Hee, Lee, Mi-Ock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122892/
https://www.ncbi.nlm.nih.gov/pubmed/35593921
http://dx.doi.org/10.1007/s00018-022-04333-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122892/
https://www.ncbi.nlm.nih.gov/pubmed/35593921
http://dx.doi.org/10.1007/s00018-022-04333-y

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