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Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins

Chemical fixations have been thought to preserve the structures of the cells or tissues. However, given that the fixatives create crosslinks or aggregate proteins, there is a possibility that these fixatives create nanoscale artefacts by aggregation of membrane proteins which move around freely to s...

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Detalles Bibliográficos
Autores principales: Ichikawa, Takehiko, Wang, Dong, Miyazawa, Keisuke, Miyata, Kazuki, Oshima, Masanobu, Fukuma, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122943/
https://www.ncbi.nlm.nih.gov/pubmed/35595960
http://dx.doi.org/10.1038/s42003-022-03437-2