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Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins
Chemical fixations have been thought to preserve the structures of the cells or tissues. However, given that the fixatives create crosslinks or aggregate proteins, there is a possibility that these fixatives create nanoscale artefacts by aggregation of membrane proteins which move around freely to s...
Autores principales: | Ichikawa, Takehiko, Wang, Dong, Miyazawa, Keisuke, Miyata, Kazuki, Oshima, Masanobu, Fukuma, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122943/ https://www.ncbi.nlm.nih.gov/pubmed/35595960 http://dx.doi.org/10.1038/s42003-022-03437-2 |
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