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Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues

The endogenous cyclic tetradecapeptide SST14 was reported to stimulate all five somatostatin receptors (SSTR1–5) for hormone release, neurotransmission, cell growth arrest and cancer suppression. Two SST14-derived short cyclic SST analogues (lanreotide or octreotide) with improved stability and long...

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Detalles Bibliográficos
Autores principales: Bo, Qing, Yang, Fan, Li, Yingge, Meng, Xianyu, Zhang, Huanhuan, Zhou, Yingxin, Ling, Shenglong, Sun, Demeng, Lv, Pei, Liu, Lei, Shi, Pan, Tian, Changlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122944/
https://www.ncbi.nlm.nih.gov/pubmed/35595746
http://dx.doi.org/10.1038/s41421-022-00405-2