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Kindlin-2 promotes Src-mediated tyrosine phosphorylation of androgen receptor and contributes to breast cancer progression

Androgen receptor (AR) signaling plays important roles in breast cancer progression. We show here that Kindlin-2, a focal adhesion protein, is critically involved in the promotion of AR signaling and breast cancer progression. Kindlin-2 physically associates with AR and Src through its two neighbori...

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Detalles Bibliográficos
Autores principales: Ma, Luyao, Tian, Yeteng, Qian, Tao, Li, Wenjun, Liu, Chengmin, Chu, Bizhu, Kong, Qian, Cai, Renwei, Bai, Panzhu, Ma, Lisha, Deng, Yi, Tian, Ruijun, Wu, Chuanyue, Sun, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122951/
https://www.ncbi.nlm.nih.gov/pubmed/35595729
http://dx.doi.org/10.1038/s41419-022-04945-z