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m6A methylated EphA2 and VEGFA through IGF2BP2/3 regulation promotes vasculogenic mimicry in colorectal cancer via PI3K/AKT and ERK1/2 signaling

Exploring the epigenetic regulation mechanism of colorectal cancer (CRC) from the perspective of N6-methyladenosine (m6A) modification may provide a new target for tumor therapy. Analysis using high-throughput RNA-seq profile from TCGA found that the gene expression of Methyltransferase-like 3 (METT...

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Detalles Bibliográficos
Autores principales: Liu, Xin, He, Hongjuan, Zhang, Fengwei, Hu, Xin, Bi, Fanqi, Li, Kai, Yu, Haoran, Zhao, Yue, Teng, Xiangqi, Li, Jiaqi, Wang, Lihong, Zhang, Yan, Wu, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122982/
https://www.ncbi.nlm.nih.gov/pubmed/35595748
http://dx.doi.org/10.1038/s41419-022-04950-2