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Codon-specific Ramachandran plots show amino acid backbone conformation depends on identity of the translated codon

Synonymous codons translate into chemically identical amino acids. Once considered inconsequential to the formation of the protein product, there is evidence to suggest that codon usage affects co-translational protein folding and the final structure of the expressed protein. Here we develop a metho...

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Detalles Bibliográficos
Autores principales: Rosenberg, Aviv A., Marx, Ailie, Bronstein, Alex M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123026/
https://www.ncbi.nlm.nih.gov/pubmed/35595777
http://dx.doi.org/10.1038/s41467-022-30390-9