Azetidine-2-Carboxylic Acid-Induced Oligodendrogliopathy: Relevance to the Pathogenesis of Multiple Sclerosis

The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro. To determine Aze effects on the mammalian CNS in vivo, adult CD1 mice were given Aze orally or intraperitoneally. Clinical...

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Detalles Bibliográficos
Autores principales: Sobel, Raymond A, Albertelli, Megan, Hinojoza, Julian R, Eaton, Mary Jane, Grimes, Kevin V, Rubenstein, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123080/
https://www.ncbi.nlm.nih.gov/pubmed/35521963
http://dx.doi.org/10.1093/jnen/nlac028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123080/
https://www.ncbi.nlm.nih.gov/pubmed/35521963
http://dx.doi.org/10.1093/jnen/nlac028

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