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A comprehensive evaluation of the potential binding poses of fentanyl and its analogs at the µ-opioid receptor

Fentanyl and its analogs are selective agonists of the µ-opioid receptor (MOR). Among novel synthetic opioids (NSOs), they dominate the recreational drug market and are the main culprits for the opioid crisis, which has been exacerbated by the COVID-19 pandemic. By taking advantage of the crystal st...

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Detalles Bibliográficos
Autores principales: Xie, Bing, Goldberg, Alexander, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123087/
https://www.ncbi.nlm.nih.gov/pubmed/35615021
http://dx.doi.org/10.1016/j.csbj.2022.05.013