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A comprehensive evaluation of the potential binding poses of fentanyl and its analogs at the µ-opioid receptor
Fentanyl and its analogs are selective agonists of the µ-opioid receptor (MOR). Among novel synthetic opioids (NSOs), they dominate the recreational drug market and are the main culprits for the opioid crisis, which has been exacerbated by the COVID-19 pandemic. By taking advantage of the crystal st...
Autores principales: | Xie, Bing, Goldberg, Alexander, Shi, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123087/ https://www.ncbi.nlm.nih.gov/pubmed/35615021 http://dx.doi.org/10.1016/j.csbj.2022.05.013 |
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