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Differences in interaction lead to the formation of different types of insulin amyloid

Insulin balls, localized insulin amyloids formed at the site of repeated insulin injections in patients with diabetes, cause poor glycemic control and cytotoxicity. Our previous study has shown that insulin forms two types of amyloids; toxic amyloid formed from the intact insulin ((i)-amyloid) and l...

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Detalles Bibliográficos
Autores principales: Mori, Wakako, Kawakami, Ryosuke, Niko, Yosuke, Haruta, Tomohiro, Imamura, Takeshi, Shiraki, Kentaro, Zako, Tamotsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123177/
https://www.ncbi.nlm.nih.gov/pubmed/35595809
http://dx.doi.org/10.1038/s41598-022-12212-6