Cargando…
Differences in interaction lead to the formation of different types of insulin amyloid
Insulin balls, localized insulin amyloids formed at the site of repeated insulin injections in patients with diabetes, cause poor glycemic control and cytotoxicity. Our previous study has shown that insulin forms two types of amyloids; toxic amyloid formed from the intact insulin ((i)-amyloid) and l...
Autores principales: | Mori, Wakako, Kawakami, Ryosuke, Niko, Yosuke, Haruta, Tomohiro, Imamura, Takeshi, Shiraki, Kentaro, Zako, Tamotsu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123177/ https://www.ncbi.nlm.nih.gov/pubmed/35595809 http://dx.doi.org/10.1038/s41598-022-12212-6 |
Ejemplares similares
-
Degradation of insulin amyloid by antibiotic minocycline and formation of toxic intermediates
por: Mori, Wakako, et al.
Publicado: (2021) -
Insulin amyloid fibrils interact directly with the NLRP3, resulting in
inflammasome activation and pyroptotic cell death
por: Mori, Wakako, et al.
Publicado: (2021) -
Inflammasome assembly is required for intracellular formation of β2-microglobulin amyloid fibrils, leading to IL-1β secretion
por: Kaneko, Naoe, et al.
Publicado: (2022) -
Insulin amyloid polymorphs: implications for iatrogenic cytotoxicity
por: Yuzu, Keisuke, et al.
Publicado: (2020) -
High-quality Fluorescence Imaging of the Human Acrosyringium Using a Transparency: Enhancing Technique and an Improved, Fluorescent Solvatochromic Pyrene Probe
por: Murakami, Masamoto, et al.
Publicado: (2020)