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Structural rearrangements allow nucleic acid discrimination by type I-D Cascade

CRISPR-Cas systems are adaptive immune systems that protect prokaryotes from foreign nucleic acids, such as bacteriophages. Two of the most prevalent CRISPR-Cas systems include type I and type III. Interestingly, the type I-D interference proteins contain characteristic features of both type I and t...

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Detalles Bibliográficos
Autores principales: Schwartz, Evan A., McBride, Tess M., Bravo, Jack P. K., Wrapp, Daniel, Fineran, Peter C., Fagerlund, Robert D., Taylor, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123187/
https://www.ncbi.nlm.nih.gov/pubmed/35595728
http://dx.doi.org/10.1038/s41467-022-30402-8