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Single-Cell Analysis of Refractory Celiac Disease Demonstrates Inter- and Intra-Patient Aberrant Cell Heterogeneity

BACKGROUND & AIMS: Refractory celiac disease type II (RCDII) is a rare indolent lymphoma in the small intestine characterized by a clonally expanded intraepithelial intracellular CD3(+)surfaceCD3(-)CD7(+)CD56(-) aberrant cell population. However, RCDII pathogenesis is ill-defined. Here, we aimed...

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Detalles Bibliográficos
Autores principales: Dieckman, Tessa, Schreurs, Mette, Mahfouz, Ahmed, Kooy-Winkelaar, Yvonne, Neefjes-Borst, Andra, Bouma, Gerd, Koning, Frits
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123272/
https://www.ncbi.nlm.nih.gov/pubmed/35338007
http://dx.doi.org/10.1016/j.jcmgh.2022.03.005